Traumatic brain injury (TBI) is a leading cause of morbidity and mortality worldwide. While many safety interventions have been implemented to reduce occurrence, the options to treat TBI post injury are severely lacking. In order to address this need, this project presents preclinical evidence on the use of tolerogenic vaccines to reduce neuro inflammation and…

Gaze shifts in sports provide important visual cues for anticipating and adapting to dynamic play situations. Volleyball athletes have been shown to rely heavily on gaze shifts from the ball to the spiker, particularly during blocking. Effective volleyball performance hinges on this gaze behavior, however, gaze shift patterns necessary for blocking success remain unclear. The…

This project aims to create an alternative to current hypothyroidism treatments through the concept of a multi-layer T4-delivering patch. This patch would be applied to the surface of the skin and diffuse transdermally into the bloodstream for a more localized delivery. The design consists of a hydrogel scaffold, about half of which will be blank…

We aim to ensure the leptin delivery system targets patients with type 1 diabetes, aiming to reduce systemic dosage delivery and benefit patients. Determine to lessen the long-term healthcare costs of preventing diabetes; this project promises improvements in patients’ overall health. Looking into the type 1 diabetes market is valued at $15.95 billion in 2024…

Our team is seeking to design an endovascular shunt system for treating obstructive hydrocephalus. Hydrocephalus occurs when cerebrospinal fluid (CSF) builds up in the brain’s ventricles, and puts pressure on the brain. This restricts blood flow and can cause damage to the brain tissue. Current treatments are highly invasive and are largely ineffective in treating…

Intravenous (IV) catheters provide an essential means for rapid, controlled drug delivery directly into the bloodstream, yet they also pose a serious risk of catheter-related bloodstream infections (CRBSIs). CRBSIs represent a significant clinical challenge, leading to patient complications, increased healthcare costs, and longer hospital stays. With a substantial market size of approximately USD 8.6 billion…

Epilepsy is a chronic neurological disorder affecting over 50 million people worldwide. Current methods for monitoring and diagnosing epilepsy are conducted through EEG data collection and manual analysis in a clinical setting. This method can be both stressful and costly for patients as well as time-consuming and inefficient for clinicians. Our team aims to produce…

Existing market solutions for breast lesion localization primarily rely on invasive devices, which can cause considerable patient discomfort and raise safety concerns among healthcare providers. These invasive options often require multiple clinic visits and involve procedures that are inconvenient and, sometimes, distressing for patients. Our solution proposes a non-invasive device that uses a controlled magnetic…

This Capstone project focuses on a soft robotic elbow brace designed to treat spasticity in patients in stroke rehabilitation therapy. It delivers real-time muscle data to occupational therapists while straightening the forearm and hand muscles. Spasticity, characterized by muscle stiffness and involuntary contractions, presents a major barrier to recovery for stroke patients, affecting both comfort…

Precision Phantoms addresses the gap in medical device calibration and validation for processing as well as in preclinical trials by creating biomimetic phantoms using composite solid gels as the foundational material that simulate the electrical, thermal and anatomical properties of human tissues. These phantoms aid accurate testing and calibration of energy-based medical devices for diagnostic…