Fall 2024
Brain NMR Metabolomics Using Extracted Liquid Samples vs Focused Beam Microwave Fixed Solid Tissues
Abstract Magic Angle Spinning (MAS) Nuclear Magnetic Resonance (NMR) Spectroscopy is known for its ability to produce sharper, more resolved peaks compared to traditional liquid chemical extraction NMR. The broad, poorly resolved peaks typically observed in liquid NMR average out in solid-state MAS, resulting in higher quality data, especially when applied to complex samples such…
Local Field Potential Modulations in the Motor Cortex Arising from Different Tactile Cues and Visual Feedback in a Mixed Reality Environment
Abstract Multisensory integration is a complex integration of multiple senses used to form percepts that are critical for interacting with one’s surroundings. Mixed reality platforms are a way to study multisensory integration. In a recent study from the lab, a mixed reality platform was used to examine effects of different tactile cues and arm visual…
Discovering the 6th Degree of Freedom: How to Incorporate the Electrode Lead in the DBS Automatic Leksell Frame Adjuster Device
Abstract Deep brain stimulation (DBS) is a neurosurgical treatment that uses electrical stimulation to targeted portions of the brain to treat conditions such as Parkinson’s disease, epilepsy, Tourettes, OCD, and obesity. The current Leksell frame Adjuster is an antiquated device that neurosurgeons have been using that is very tedious and outdated for them. I will…
Assessing Cognitive Performance during Dynamic Activities with Varying Insole Textures
Abstract Assessing the data quality and overall presence of current excited signal is an important stage of screening and processing the data produced from Magnetic Resonance Electrical Impedance Tomography (MREIT) experiments. To do this, Signal to Noise (SNR) analysis and two methods of subtractive comparison were utilized. The data analyzed consisted of previously collected MREIT…
Similarity of Subtracted Current Excitation of Off-Plane Magnetic Resonance Electrical Impedance Tomography
Abstract Assessing the data quality and overall presence of current excited signal is an important stage of screening and processing the data produced from Magnetic Resonance Electrical Impedance Tomography (MREIT) experiments. To do this, Signal to Noise (SNR) analysis and two methods of subtractive comparison were utilized. The data analyzed consisted of previously collected MREIT…
Quantifying Stress and Cognitive Responses During Auditory Stressors Exposure
Abstract Stress significantly impacts cognitive function, health, and overall well-being, with auditory stressors, such as occupational noise, posing a frequent challenge in both professional and personal environments. This study investigates the relationship between auditory stress, physiological stress responses measured through Galvanic Skin Response (GSR), and cognitive performance using Stroop and Hopkins Verbal Learning Task (HVLT)…
Characterization and Tracking of Immune Cell Dynamics on a Placenta-on-a-Chip Platform
Abstract Early gestation placental immunology and nutrient transport have been poorly understood due to limitations in ethical constraints and inadequate animal model replication. Current placenta-on-a-chip models offer a controlled approach for placental studies but lack precision in early gestation stages. Before developing a fully 3D printed microfluidic chip that models early placental interactions between placental…
Innovative Footwear Solutions for Active Recovery: A Practical Approach to Enhancing Peripheral Circulation
Abstract The importance of effective recovery strategies in reducing fatigue, enhancing performance, and preventing injuries has driven interest in evaluating innovative footwear solutions. This study aimed to investigate the role of different footwear types in enhancing peripheral circulation, focusing on their ability to influence blood oxygenation and delivery. By analyzing changes in oxygenated hemoglobin (O2Hb)…
Design Fabrication of IoT-Enabled Infusion Syringe Pump and Biosensing System for Telemedicine and Healthcare
Abstract The advancement of medical technology has led to the development of innovative devices aimed at enhancing patient care and monitoring. This project focuses on the design and fabrication of an IoT-enabled infusion syringe pump integrated with a biosensing system for telemedicine applications. The system combines Arduino-based technology, a ball screw linear guide for precise…
Automating the Leksell Frame Adjustor: Incorporating Phi and Theta Movement to Achieve 5 Degrees of Freedom and Trajectory Planning of the Device
Abstract The Leksell Frame is a device used in stereotactic surgery, commonly for Deep Brain Surgery (DBS). The device requires manual adjustments and soft tapping using a screw to set the target location on the brain. It is prone to human error, limiting its precision and efficiency. The aim of the project is to modernize…