Evolution of Drug Encapsulation Methods in PDMS films for RAC2 Signaling Inhibition

Biomedical Engineering

Aasim Khan

Abstract

This project explores novel formulations of PDMS-based films incorporating various encapsulation agents to enable controlled and sustained drug release. By comparing the effects of water, DCM, and an Ionic liquid on drug loading efficiency and release kinetics, the study aims to optimize polymer-drug interactions for biomedical use. Future applications include tuning these formulations for specific therapeutic needs, such as anti-inflammatory or anti-fibrotic drug delivery systems.

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