Biomedical Engineering

E-Lumenate: Optimizing Treatment of Eosinophilic Esophagitis Using an Internal Phototherapy Device

E-Lumenate is a minimally invasive phototherapy device designed to address the need for an effective, localized treatment for Eosinophilic Esophagitis (EoE), a chronic, inflammatory condition caused by excess eosinophilic cells within the esophageal tissue. EoE has increased fivefold since 2009, affecting about 1 in 700 people in the United States. Current treatments, including corticosteroids, proton…

Uterra by Illumigyn: A novel uterine manipulator for laparoscopic hysterectomies with an illuminated colpotomy cup

Over 400,000 hysterectomies are performed annually in the U.S., and visibility limitations remain a leading challenge contributing to more surgical complications. The primary clinical challenge identified by stakeholders, including gynecologic surgeons, was the need for improved visualization during laparoscopic hysterectomies, particularly at the colpotomy incision site. Moreover, the market for uterine manipulators is projected to…

Mechanical Spring-Loaded Pinch Roller Device for Precision Guidewire Torque Transmission in Endovascular Procedures

Endovascular procedures require controlled guidewire manipulation, however, current torque devices are often manual, causing inconsistent rotation, slippage, and operator fatigue [1]. There exists a clinical need for improved torque precision, reduced hand fatigue, and safer wire handling, as established via surgeon surveys and stakeholder interviews. More than a million endovascular procedures are performed annually, and…

Bioresorbable Intravaginal Scaffold Delivering Lauramide Arginine Ethyl Ester as an Adjunct to Antibiotic Therapy for Recurrent BV Prevention

Bacterial vaginosis (BV) is the most prevalent vaginal infection worldwide, impacting over 21 million women annually in the U.S. and contributing to increased susceptibility to sexually transmitted infections and adverse pregnancy outcomes. Despite antibiotic treatments such as metronidazole, recurrence rates exceed 50% within six months due to persistent Gardnerella vaginalis biofilms and failure to reestablish…

Wireless, Battery-Free Intraoral Deep Brain Stimulation for Trigeminal Neuralgia

This paper presents the design, development, and experimentation of a wireless, battery-free neural stimulation system utilizing an intraoral pathway for power delivery to deep brain targets for the treatment of trigeminal neuralgia. Traditional neuromodulation systems require implantable pulse generators and wired leads. This introduces surgical risks and hardware complications. To address these limitations, a resonant…

Method to Measure Intracranial Pressure Wirelessly Using Remote Powering by Ultrasound

Over 14 million people are affected by increased intracranial pressure (ICP) due to traumatic brain injury or conditions like hydrocephalus, which causes excess cerebrospinal fluid in the brain. This research aims to develop and test a novel remote impedance measurement system (RIMS) that uses wireless power transfer between an external ultrasound emitter and an implanted…

Modeling the Relationship Between Triathletes Split Times and Race Performance

This project analyzed real-world race data from collegiate triathletes to identify which race segments best predict overall sprint triathlon performance. A multiple linear regression model revealed that the bike split had the strongest influence on total time, with transitions also contributing meaningfully. Using these insights, an interactive tool was developed in Python to help athletes…

Mapping Haptic-Induced Zonal Brain Activation – An fNIRS Study

This study investigates whether uncomfortable footwear increases neural activation in the primary somatosensory cortex by measuring brain hemodynamic activity via fNIRS (Functional Near-Infrared Spectroscopy). Participants first walked on a treadmill for 5 minutes wearing their regular shoes, then repeated the trial after inserting provided uncomfortable shoe padding, while oxygenated hemoglobin levels, a key indicator of…

Biomechanical Analysis of Center of Mass During Martial Arts

The goal of this study is to take new individuals, undeveloped in the Korean martial art Tang Soo Do, and track their center of mass acceleration variability using Motion Capture technology with Ki Gong meditation acting as an intervention. Video Research poster View the poster Health

Assess the Impact of Air Quality on Individual Cognition and Motor Capability

The project looked into the effects of air quality specifically PM 2.5 on cognitive and motor scores. Physics based motor task game “Super G” was played by 878 participants which were linked with their zip code to determine the effects of environmental data and participant performance. The goal was to investigate whether poor air quality…