Project sponsor

Mayo Clinic

Logo for Mayo Clinic

Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. Relentless research turns into earlier diagnoses and new cures, inspiring hope in those who need it most.

Website

Spring 2026

Portable Smartphone Adapter for Imaging the Anterior and Posterior Segments of the Eye

Eye-related complaints are increasingly prevalent in emergency departments, where access to ophthalmologists is often limited. This gap can delay diagnosis and treatment, particularly for conditions requiring timely evaluation. A rapid, accessible method for capturing and sharing diagnostic-quality eye images would improve triage efficiency and support remote clinical decision-making in both hospital and resource-limited settings. TeleVision…

Read more

Systemic Sclerosis Calcinosis Outcomes with Wearable Ultrasound Technology (SCOUT)

Calcinosis, a debilitating complication of systemic sclerosis (SSc), affects up to 40% of patients and is typically identified only after symptom onset, when tissue damage and pain have already progressed. Current diagnostic workflows rely on reactive, high-cost imaging modalities such as MRI or CT, creating barriers to early detection and limiting routine screening in outpatient…

Read more

Clinical Communication Platform

Effective clinical communication is central to patient outcomes, yet nearly 50% of medical malpractice claims cite communication failures as a contributing factor. Current training relies on expensive, unscalable actor-based simulations that are cost-prohibitive. There is a critical need for an automated, data-driven coaching tool that provides objective, ongoing feedback on real patient interactions to reduce…

Read more

Omni-Axis: Overbed Table Improvement

Hospitalized adult inpatients and clinical staff are poorly served by current overbed table designs, which lack maneuverability, ergonomic adaptability, and adequate storage. Surveys of Mayo Clinic staff confirm this need, with over 96% reporting difficulty moving existing models, compromising patient independence and obstructing critical workflow during emergencies. The AtlasWorks Omni-Axis Overbed Table reimagines the conventional…

Read more

E-Lumenate: Optimizing Treatment of Eosinophilic Esophagitis Using an Internal Phototherapy Device

Eosinophilic Esophagitis (EoE) is a chronic inflammatory condition characterized by immune-mediated damage to esophageal tissue. This inflammation leads to symptoms such as dysphagia, food impaction, and structural changes over time. Current treatment strategies for EoE include dietary restrictions, proton pump inhibitors, and glucocorticoids, but they are often burdensome, inconsistent, and associated with many long-term side…

Read more

Fall 2025

Portable Smartphone Adapter for Imaging the Anterior and Posterior Segments of the Eye

Eye-related complaints are increasingly prevalent in emergency departments, where access to ophthalmologists is often limited. This gap can delay diagnosis and treatment, particularly for conditions requiring timely evaluation. A rapid, accessible method for capturing and sharing diagnostic-quality eye images would improve triage efficiency and support remote clinical decision-making in both hospital and resource-limited settings. TeleVision…

Read more

Systemic Sclerosis Calcinosis Outcomes with Wearable Ultrasound Technology (SCOUT)

Calcinosis, a debilitating complication of systemic sclerosis (SSc), affects up to 40% of patients and is typically identified only after symptom onset, when tissue damage and pain have already progressed. Current diagnostic workflows rely on reactive, high-cost imaging modalities such as MRI or CT, creating barriers to early detection and limiting routine screening in outpatient…

Read more

Computer Vision Quality Assurance for Medical Linear Accelerators

Each year, millions of patients undergo radiation treatment utilizing medical linear accelerators (linacs) due to their noninvasiveness and submillimeter precision. Although linacs offer innovative and advanced treatment plans, some mechanical QA procedures remain subjective due to human error. One of these being the verification of the optical distance indicator and vertical offset between the linac…

Read more

Clinical Communication Platform

Effective clinical communication is central to patient outcomes, yet nearly 50% of medical malpractice claims cite communication failures as a contributing factor. Current training relies on expensive, unscalable actor-based simulations that are cost-prohibitive. There is a critical need for an automated, data-driven coaching tool that provides objective, ongoing feedback on real patient interactions to reduce…

Read more

Omni-Axis: Overbed Table Improvement

Hospitalized adult inpatients and clinical staff are poorly served by current overbed table designs, which lack maneuverability, ergonomic adaptability, and adequate storage. Surveys of Mayo Clinic staff confirm this need, with over 96% reporting difficulty moving existing models, compromising patient independence and obstructing critical workflow during emergencies. The AtlasWorks Omni-Axis Overbed Table reimagines the conventional…

Read more

E-Lumenate: Optimizing Treatment of Eosinophilic Esophagitis Using an Internal Phototherapy Device

Eosinophilic Esophagitis (EoE) is a chronic inflammatory condition characterized by immune-mediated damage to esophageal tissue. This inflammation leads to symptoms such as dysphagia, food impaction, and structural changes over time. Current treatment strategies for EoE include dietary restrictions, proton pump inhibitors, and glucocorticoids, but they are often burdensome, inconsistent, and associated with many long-term side…

Read more

Fall 2024

Anvitha Doddipalli Joshua Hanson Ethan Hurt Jessica Miron

Development of the Pocket Doppler for AI Cloud Connectivity

Peripheral artery disease (PAD) is the buildup of plaque in a patient’s peripheral arteries, most common in the legs and feet. PAD currently affects about 10 million Americans and is an underserved disease as there is no outstanding treatment. Early detection is the best treatment for PAD as it enables patients to make healthy lifestyle…

Read more
Husain Alnajar Arvin Brar Karsten Lantz Narendiren Raghu Srikar Samavedam

AIS Brace Improvement

Adolescent idiopathic scoliosis (AIS) affects 2-4% of children aged 10-18 globally, with untreated moderate to severe cases potentially leading to significant health complications. Bracing is a non-invasive method to prevent curve progression, but patient compliance remains low, often averaging just 33-77% of the recommended wear time. Discomfort, movement restrictions, appearance concerns, and psychosocial factors primarily…

Read more
Davin Dai Aidee Beltran Quiroz Alex Wada Franchesca Huynh

Asthma Inhaler

The PulmonUs team is designing a refillable multi use dry powder inhaler that is biodegradable and also easier to use for patients across all ages. The current aerosol inhalers that are available on the market utilize hydrofluoroalkanes (HFAs) to deliver asthma medication to patients. Recent emerging studies have shown that the HFAs in a single…

Read more
Kyle Richardson Bret Jonah Ashby Cody Haws Benjamin Langford

Wearable Technology for Vascular Health

The ExecuWear Biometric Sleeve is a wearable device designed to address the health challenges of high-performing professionals and executives who spend extended periods in sedentary, high-stress environments, increasing their risk of cardiovascular complications. This device focuses on continuous monitoring of biometric data, including blood pressure, heart rate, and sedentary time, to provide real-time health insights….

Read more
Shreya Anandan Jasmine Aviles Mena Natalie Butterfield Alina Puig Shreya Sharma

Larnyx Tissue Engineering

Idiopathic subglottic stenosis (iSGS) is a chronic inflammatory condition characterized by abnormal wound healing around the subglottis and tracheal region. Excessive fibrosis causes ECM deposition in the area, leading to tissue stiffness and narrowing of the passage. There is no permanent solution and current treatment solutions are surgically removing the scar tissue with topical medication;…

Read more

Spring 2025

Anvitha Doddipalli Joshua Hanson Ethan Hurt Jessica Miron

Development of the Pocket Doppler for AI Cloud Connectivity

Peripheral artery disease (PAD) is the buildup of plaque in a patient’s peripheral arteries namely the legs and feet. PAD currently affects more than 10 million Americans and is an underserved disease as most patients are asymptomatic and there is no outstanding cure. The best available treatment for PAD is to detect it early, as…

Read more
Husain Alnajar Arvin Brar Karsten Lantz Narendiren Raghu Srikar Samavedam

AIS Brace Improvement

Adolescent idiopathic scoliosis (AIS) affects about 2–4% of kids between 10 and 18. If not treated early, it can lead to serious health problems. Bracing is a common way to stop the curve from getting worse, but many kids don’t wear their brace as much as they should. It’s usually because it’s uncomfortable, hard to…

Read more
Davin Dai Aidee Beltran Quiroz Alex Wada Franchesca Huynh

Asthma Inhaler

The PulmonUs team designed ReLung, a refillable dry powder inhaler that is biodegradable and also easier to use for patients. Current aerosol inhalers that are available on the market utilize hydrofluoroalkanes (HFAs) to deliver asthma medication to patients. Recent emerging studies have shown that the HFAs in a single asthma inhaler emits as much carbon…

Read more
Kyle Richardson Bret Jonah Ashby Cody Haws Benjamin Langford

Wearable Technology for Vascular Health

The ExecuWear Biometric Sleeve is a wearable device designed to address the health challenges of high-performing professionals and executives who spend extended periods in sedentary, high-stress environments, increasing their risk of cardiovascular complications. This device focuses on continuous monitoring of biometric data, specifically blood pressure as well asheart rate and sedentary time, to provide real-time…

Read more
Shreya Anandan Jasmine Aviles Mena Natalie Butterfield Alina Puig Shreya Sharma

Larnyx Tissue Engineering

Idiopathic subglottic stenosis (iSGS) is a chronic inflammatory condition characterized by abnormal wound healing around the subglottis and tracheal region. Excessive fibrosis causes ECM deposition in the area, leading to tissue stiffness and narrowing of the passage. There is no permanent solution, and current treatment solutions involve surgically removing the scar tissue with topical medication;…

Read more
Anika Attaluri Ava Claire Lariego Anushka Limaye Neha Shakir Tina Ton

Modular Optical System that Acts as an Adapter for Smart Devices

This project aims to develop a low-cost, smartphone-adaptable ophthalmic imaging device that can be used to improve access and quality of eye care, particularly in emergency departments (i.e., triage contexts) and resource-limited settings (e.g., remote and/or rural clinics). Current tabletop ophthalmic imaging tools can be expensive and bulky, and thus not widely or easily available…

Read more
Ella Gleason, Allyiah Gomez, Kylie Hartana, Nicholas Steele, and Isabella Valli-Doherty

Developing an Automated, Continuous Counting Inventory Module for Medication Management and Drug Diversion Prevention

PharmAccount is developing an innovative module that integrates continuous medication counting into medication management systems like the BD Pyxis™ MedStation to address inefficiencies and vulnerabilities in hospital medication management. Hospitals face challenges in maintaining accurate medication inventory, preventing drug diversion, and reducing administrative burdens on nursing staff. The reliance on manual blind counts is time-consuming,…

Read more
Capstones Logo