Mayo Clinic

Eye-related concerns are increasingly prevalent in emergency departments, but ophthalmologists are often not available in such settings. A quick and effective method for communicating eye concerns would aid in triage and allow for faster treatment in emergency departments. TeleVision aims to improve ophthalmic diagnosis in emergency departments and resource-limited settings by developing a smartphone-compatible imaging…

Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by progressive fibrosis of the skin and internal organs. A debilitating complication of SSc is calcinosis: the deposition of calcium hydroxyapatite in soft tissue. These deposits, which most commonly develop in the hands/fingers, can cause severe pain, ulceration, infection, and functional impairment, yet remain difficult to…

Radiation therapy is a non-invasive and highly versatile approach to combat tumor growth in cancer patients by utilizing high-energy X-ray beams targeted towards tumor tissues to inhibit growth. Radiation therapy is able to suppress tumor growth in almost all areas of the human body, making it a widely applicable treatment method. Medical linear accelerators (linacs)…

Effective clinician–patient communication is a critical determinant of patient outcomes, clinician burnout, and overall quality of care, yet clinicians currently lack objective, scalable tools to evaluate their communication behaviors outside of subjective mentorship. To address this gap, our team is developing a post-encounter multi-modal analysis platform that provides clinicians with rapid, data-driven feedback on empathetic…

Hospitalized adult inpatients and clinical staff are poorly served by current overbed tables, which are defined by their lack of maneuverability, ergonomic features and storage options. Clinical feedback gathered directly from Mayo Clinic Staff confirms this need with over 96% of staff reporting that the existing table models are difficult to move, compromising patient independence…

E-Lumenate is a minimally invasive phototherapy device designed to address the need for an effective, localized treatment for Eosinophilic Esophagitis (EoE), a chronic, inflammatory condition caused by excess eosinophilic cells within the esophageal tissue. EoE has increased fivefold since 2009, affecting about 1 in 700 people in the United States. Current treatments, including corticosteroids, proton…

Peripheral artery disease (PAD) is the buildup of plaque in a patient’s peripheral arteries, most common in the legs and feet. PAD currently affects about 10 million Americans and is an underserved disease as there is no outstanding treatment. Early detection is the best treatment for PAD as it enables patients to make healthy lifestyle…

Adolescent idiopathic scoliosis (AIS) affects 2-4% of children aged 10-18 globally, with untreated moderate to severe cases potentially leading to significant health complications. Bracing is a non-invasive method to prevent curve progression, but patient compliance remains low, often averaging just 33-77% of the recommended wear time. Discomfort, movement restrictions, appearance concerns, and psychosocial factors primarily…

The PulmonUs team is designing a refillable multi use dry powder inhaler that is biodegradable and also easier to use for patients across all ages. The current aerosol inhalers that are available on the market utilize hydrofluoroalkanes (HFAs) to deliver asthma medication to patients. Recent emerging studies have shown that the HFAs in a single…

The ExecuWear Biometric Sleeve is a wearable device designed to address the health challenges of high-performing professionals and executives who spend extended periods in sedentary, high-stress environments, increasing their risk of cardiovascular complications. This device focuses on continuous monitoring of biometric data, including blood pressure, heart rate, and sedentary time, to provide real-time health insights….

Idiopathic subglottic stenosis (iSGS) is a chronic inflammatory condition characterized by abnormal wound healing around the subglottis and tracheal region. Excessive fibrosis causes ECM deposition in the area, leading to tissue stiffness and narrowing of the passage. There is no permanent solution and current treatment solutions are surgically removing the scar tissue with topical medication;…

Peripheral artery disease (PAD) is the buildup of plaque in a patient’s peripheral arteries namely the legs and feet. PAD currently affects more than 10 million Americans and is an underserved disease as most patients are asymptomatic and there is no outstanding cure. The best available treatment for PAD is to detect it early, as…

Adolescent idiopathic scoliosis (AIS) affects about 2–4% of kids between 10 and 18. If not treated early, it can lead to serious health problems. Bracing is a common way to stop the curve from getting worse, but many kids don’t wear their brace as much as they should. It’s usually because it’s uncomfortable, hard to…

The PulmonUs team designed ReLung, a refillable dry powder inhaler that is biodegradable and also easier to use for patients. Current aerosol inhalers that are available on the market utilize hydrofluoroalkanes (HFAs) to deliver asthma medication to patients. Recent emerging studies have shown that the HFAs in a single asthma inhaler emits as much carbon…

The ExecuWear Biometric Sleeve is a wearable device designed to address the health challenges of high-performing professionals and executives who spend extended periods in sedentary, high-stress environments, increasing their risk of cardiovascular complications. This device focuses on continuous monitoring of biometric data, specifically blood pressure as well asheart rate and sedentary time, to provide real-time…

Idiopathic subglottic stenosis (iSGS) is a chronic inflammatory condition characterized by abnormal wound healing around the subglottis and tracheal region. Excessive fibrosis causes ECM deposition in the area, leading to tissue stiffness and narrowing of the passage. There is no permanent solution, and current treatment solutions involve surgically removing the scar tissue with topical medication;…

This project aims to develop a low-cost, smartphone-adaptable ophthalmic imaging device that can be used to improve access and quality of eye care, particularly in emergency departments (i.e., triage contexts) and resource-limited settings (e.g., remote and/or rural clinics). Current tabletop ophthalmic imaging tools can be expensive and bulky, and thus not widely or easily available…

PharmAccount is developing an innovative module that integrates continuous medication counting into medication management systems like the BD Pyxis™ MedStation to address inefficiencies and vulnerabilities in hospital medication management. Hospitals face challenges in maintaining accurate medication inventory, preventing drug diversion, and reducing administrative burdens on nursing staff. The reliance on manual blind counts is time-consuming,…