Undergraduate

Fetal Monitoring Signal Optimization Device

Despite being the clinical standard and a primary means of intrapartum assessment, current fetal monitoring devices have extremely high false positive rates (up to 99% for fetal distress signs like fetal acidosis). This means clinicians are often reacting to signals that don’t reflect the baby’s true condition. This not only creates confusion but also causes…

Reimagined Tenaculum

Cervical stabilization during gynecological procedures commonly relies on traditional tenacula, which use sharp hooks to grasp tissue. The current tenaculum, modeled after a civil-war era device designed to extract bullets from soldiers’ bodies, is often associated with tissue trauma, bleeding, and severe pain. There is a clear clinical need for a less invasive solution that…

Standardized MRSI Data Analysis Platform (MAPS)

Magnetic Resonance Spectroscopic Imaging (MRSI) provides valuable metabolic information for diagnosing and monitoring neurological conditions; however, its clinical and research use is limited by fragmented, non-standardized analysis workflows. Differences in scanner vendor formats require users to manually convert files, resolve metadata inconsistencies, and rely on multiple software tools, slowing data interpretation, increasing error risk, and…

E-Lumenate: Optimizing Treatment of Eosinophilic Esophagitis Using an Internal Phototherapy Device

Eosinophilic Esophagitis (EoE) is a chronic inflammatory condition characterized by immune-mediated damage to esophageal tissue. This inflammation leads to symptoms such as dysphagia, food impaction, and structural changes over time. Current treatment strategies for EoE include dietary restrictions, proton pump inhibitors, and glucocorticoids, but they are often burdensome, inconsistent, and associated with many long-term side…

Uterra by Illumigyn: A novel uterine manipulator for laparoscopic hysterectomies with an illuminated colpotomy cup

Over 400,000 hysterectomies are performed annually in the United States, yet limited intraoperative visualization remains a significant contributor to surgical complications. Surgeons frequently report difficulty visualizing the cervical-vaginal junction during colpotomy, increasing the risk of injury to surrounding structures such as the bladder and ureters. Current uterine manipulators lack integrated illumination, creating a critical unmet…

Mechanical Spring-Loaded Pinch Roller Device for Precision Guidewire Torque Transmission in Endovascular Procedures

Endovascular procedures require controlled guidewire manipulation; however, manual torque devices often cause inconsistent rotation, slippage, and operator fatigue [1]. These limitations can lead to procedural delays and complications. Surgeon surveys and stakeholder interviews show clinical need for improved torque precision, reduced fatigue, and safer wire handling. There are over 1 million annual endovascular procedures; demand…

Bioresorbable Intravaginal Scaffold Delivering Lauramide Arginine Ethyl Ester as an Adjunct to Antibiotic Therapy for Recurrent BV Prevention

Bacterial vaginosis (BV) affects approximately 30% of women worldwide, with up to 80% of patients experiencing recurrence within one year of treatment. Current therapies, including antibiotics and over-the-counter treatments, often fail to address the underlying cause of recurrence due to bacterial biofilm formation and disruption of the protective vaginal microbiome. This leads to repeated infections,…

Modeling the Relationship Between Triathletes Split Times and Race Performance

This project analyzed real-world race data from collegiate triathletes to identify which race segments best predict overall sprint triathlon performance. A multiple linear regression model revealed that the bike split had the strongest influence on total time, with transitions also contributing meaningfully. Using these insights, an interactive tool was developed in Python to help athletes…

Aileene Arias Rebecca Samuel

Drug Dispensing Biofilm

Hypothyroidism is an autoimmune disease in which the hormone secreting part of the thyroid is destroyed and therefore unable to regulate metabolism and growth. Levothyroxine is an oral treatment which helps decrease Thyroid Secreting Hormone (TSH), however it contains many obstacles, from simply remembering to take the medication to reactions caused by composition. Consequently, 35-60%…

Rayan Alam Catherine Andre Damien Berdeaux Brayan Chojolan

Leptin Infusion for Type 1 Diabetes

Our mission is to ensure the proper leptin delivery system targets patients with type 1 diabetes, aiming to reduce systemic dosage delivery and benefit patients. Determined to lessen the long-term healthcare costs, this project promises improvements in patients’ overall health. The type 1 diabetes market has $15.95 billion in 2024 and in the U.S, a…