Capstones

A student project

Immune-Active Ionic Liquid (HistaGE) for Transdermal Delivery of Histamine in Diabetic Wound Healing

Diabetic foot ulcers are difficult to heal due to impaired blood circulation, chronic inflammation, and the strong barrier function of the stratum corneum, which limits the effectiveness of topical therapies. Histamine is a vasodilatory and immune-active molecule with potential to enhance local perfusion and support tissue repair, but its therapeutic use requires a formulation capable…

Flexible Dipole Coil Array Design for Efficient Performance of Head and Neck Imaging at 7T MRI

Dipole antennas are being widely used in ultra-high field (UHF) MRI systems due to their deeper penetration depth of the transmit magnetic field (B1). However, traditional rigid dipole designs do not conform well to the highly curved anatomical regions such as neck, wrist, shoulder, etc., resulting in reduced electromagnetic coupling in tissues, increased localized electric-field…

Development of a Multi-Point Foot Pressure Sensing System for In-Home Rehabilitation Monitoring

Home-based rehabilitation post orthopedic lower-extremity interventions is difficult to monitor objectively, as clinic-based gait labs are expensive, inaccessible for frequent use, and impractical for everyday settings. Patients also often have no clear feedback on whether they are performing prescribed exercises correctly, which may slow recovery and increase the risk of re-injury. This study aims to…

Effects of Varying Spatial Disparities on Multisensory Integration During Movement Planning

Proprioception is essential for body awareness and motor planning; however, its role in multisensory integration during movement planning remains poorly understood. Most existing tests only assess conscious proprioception through position-matching and localization tasks, overlooking the role of proprioception in movement planning, which occurs at a largely unconscious level. We recently developed a method to reverse…

Emotion Aware Tactile Feedback for Deaf Users in Live Acoustic Environments

Individuals with profound hearing impairment often face difficulty experiencing the emotional richness of live acoustic environments such as concerts. Although assistive technologies improve communication, they frequently fail to reproduce the subtle, emotional characteristics of sound essential for a deeply immersive experience. Current haptic feedback devices typically convert sound into vibrations using a unidirectional transformation of…

Endoscopic Next Generation Tissue-Adhesive Tattoo (TAT2) Ink Delivery System

Tissue marking, or tattooing, is used during endoscopic procedures to identify lesions for follow-up and surgical resection. However, existing tattoo inks diffuse extensively, reducing the accuracy of later localization. Tissue-Adhesive Tattoo, Generation 2 (TAT2) is a novel mucoadhesive ink that improves spot containment by more than 90% compared with current clinical inks. Although TAT2 enables…

Decision Making Under Uncertainty with Information Overload

Information overload is a growing concern in manufacturing environments where operators must make rapid decisions under conditions of uncertainty, ambiguity, and escalating task demands. This study investigated how progressively degraded instructions and increasing informational load affect cognitive performance and physiological stress during a simulated assembly task. Ten participants completed a 49-step digital LEGO assembly set…

4-channel array flexible coil for Wrist MRI

Magnetic Resonance Imaging (MRI) of the wrist is difficult because the wrist has a complicated structure and the limitations of the conventional rigid radiofrequency (RF) coils. This research investigates the design and electromagnetic performance of a 4-channel flexible RF coil array intended to improve high-field (7T) wrist MRI imaging. The primary aim is to evaluate…

Antioxidant Polysulfide Matrices with Tunable Bioresorption for Diabetic Foot Ulcers

Of millions of individuals in the U.S. with diabetes, a large percentage will suffer from diabetic foot ulcers—chronic, non-healing wounds that can lead to amputation and death. Available remedies for diabetic foot ulcers include topical therapies or scaffold-based wound dressings. Despite availability, current solutions do not provide sufficient antioxidant release to counteract oxidative stress that…

Miraculous: A Python Tool for Plantar Pressure Analysis

Plantar pressure analysis tools are commonly used to characterize a variety of gait related pathologies and to track healing progress. Commercial plantar pressure software tools are often expensive and non-modifiable. This project presents Miraculous, an open-source Python tool which allows researchers and clinicians to view, modify, and add to stock data processing pipelines and metric…