MRI Coil Blanket

Abstract

Magnetic Resonance Imaging (MRI) is a critical tool in the early detection and diagnosis of breast cancer. However, traditional breast coils can be rigid, uncomfortable, and not optimized for patient diversity in body types and anatomy. This project aims to develop a flexible and patient-friendly MRI coil blanket specifically designed for breast imaging. The proposed solution enhances comfort, adaptability, and image quality while considering manufacturability and cost- effectiveness for clinical adoption.

The project began with research on user needs involving clinicians, radiologists, and patients to understand current limitations in breast MRI coil designs. Following concept generation and screening, the team selected flexible and rigid copper wire for coil prototyping. Comparative analysis was conducted using both coil types. An agar-based phantom was created to simulate breast tissue, and imaging was performed using a 9.4T MRI system. To extend testing to biological tissue, imaging of a rat’s brain was also conducted. Standard deviation of background noise and average signal intensity were extracted from the images to calculate and compare the SNR for each coil type.

Preliminary SNR analysis revealed that the flexible coil demonstrated higher signal performance comparable to rigid coils, in addition to improved conformability and anatomical fit. The flexible copper wire coil maintained consistent signal capture across variable shapes, supporting its feasibility for future blanket-style designs. While variability existed across image regions, the flexible coil showed promise in improving imaging uniformity and patient experience. Although the full flexible coil blanket was not completed during the capstone project, the comparative analysis provided key performance data on SNR between flexible and rigid coil designs. The findings support continued development of a flexible coil array for breast imaging, emphasizing patient comfort without compromising image quality. Future work will focus on finalizing the blanket build, conducting expanded phantom and tissue testing, and aligning with clinical and regulatory standards for translational use.

Next steps include finalizing the construction of the full coil blanket and integrating the flexible coil array into a wearable, patient-friendly format. Further testing will be conducted with advanced phantom models that more accurately simulate breast tissue heterogeneity, followed by expanded in vivo studies to evaluate clinical imaging quality. Additionally, optimization of coil geometry, circuit integration, and compatibility with clinical MRI systems will be prioritized. Long- term goals include regulatory pathway analysis, collaboration with radiologists for user feedback, and preparation for potential pilot testing in a clinical setting.

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