Characterization of Microcarrier Based Hipsc Derived Neurons for Alzheimer’s Disease Studies

Abstract

This study created a scalable microcarrier-based technology for converting hiPSCs into fully developed neurons for Alzheimer’s disease research. Neural progenitor cells were grown and differentiated for 40 days before being enzymatically separated into healthy single-cell suspensions. Immunofluorescence and calcium imaging validated neuronal identity and function, allowing for use in disease models and medication testing.

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