The Barbara Smith Lab’s Fluorescence-Guided Electrophysiology (FGE) System was created to identify neuronal subtypes inside the brain, an ongoing goal due to the imaging constraints of current systems caused by light attenuation. One area of improvement for the FGE system is the common misalignment of the optics port during fiber replacements. To mitigate this issue,…

This project investigates the physiological effects of wearing exoskeletal boots (exoboots) during extended walking in fit individuals. By measuring heart rate and oxygen consumption across different walking conditions—flat vs. incline terrain and with vs. without exoboots—the study aims to assess whether exoboot use contributes to increased fatigue. The findings are intended to inform the potential…

Hypothyroidism is an autoimmune disease in which the hormone secreting part of the thyroid is destroyed and therefore unable to regulate metabolism and growth. Levothyroxine is an oral treatment which helps decrease Thyroid Secreting Hormone (TSH), however it contains many obstacles, from simply remembering to take the medication to reactions caused by composition. Consequently, 35-60%…

Our mission is to ensure the proper leptin delivery system targets patients with type 1 diabetes, aiming to reduce systemic dosage delivery and benefit patients. Determined to lessen the long-term healthcare costs, this project promises improvements in patients’ overall health. The type 1 diabetes market has $15.95 billion in 2024 and in the U.S, a…

Our capstone team has worked in order to develop a 3-dimensional steerable catheter system for the placement of an endovascular shunt to treat obstructive hydrocephalus. Hydrocephalus occurs when a buildup of Cerebrospinal Fluid (CSF) in the brain’s ventricles causes them to expand, restricting blood flow to surrounding brain tissue. Current solutions often involve intense surgical…

Intravenous (IV) catheters are critical for delivering medications directly into the bloodstream, but they pose a significant risk of catheter-related bloodstream infections (CRBSIs), which can lead to severe complications, prolonged hospital stays, and increased healthcare costs. With the IV catheter market projected to grow from USD 8.6 billion in 2022 to USD 17.8 billion by…

Epilepsy diagnosis often relies on manual interpretation of EEG data, a process that is time-consuming, prone to error, and difficult to scale. Our project addresses this by developing a machine learning model capable of detecting epileptic events in EEG signals with accuracy and speed. We trained the model using a combination of internally collected EEG…

Current breast lesion localization methods, such as wire and radioactive seed placements, present several challenges—including patient discomfort, logistical complexity, and procedural risks. These invasive techniques often require pre-operative scheduling constraints, multiple clinic visits, and increased anxiety for patients. To address these limitations, our team has developed SONAR, a non-invasive breast lesion localization solution designed to…

The Anti-Spasticity Soft Robotic Elbow Brace is designed to treat spasticity in patients in stroke rehabilitation therapy. It delivers real-time muscle EMG data to occupational therapists while straightening the forearm muscles through a Bowden Cable System. Spasticity, characterized by muscle stiffness and involuntary contractions, presents a significant barrier to recovery for stroke patients, affecting both…

Precision Phantoms addresses the gap in medical device tuning and calibration by offering biomimetic phantoms made from solid gels with varying concentrations of electrical property modifiers as the foundational material that simulates the electrical properties of human tissues. These phantoms aid in accurate tuning and calibration of energy-based medical devices for diagnostic and therapeutic purposes….